PUBLISHED WORK
Sara Carvalhal Lab Findings
LATEST FINDINGS
Ferreira, A., Calado, S.M., Jorge, X., de Lange, J., Carvalhal, S. (2024) Generation and characterization of two isogenic induced pluripotent stem cell lines from a young female with microcephaly carrying a compound heterozygous mutation in BUB1 gene. Stem Cell Research 81, 103594. DOI: 10.1016/j.scr.2024.103594.
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Carvalhal, S.; Bader, I.; Rooimans, M.A.; Oostra, A.B.; Balk, J.A.; Feichtinger, R.J.; Beichler, C.; Speicher, M.R.; van Hagen, J.M.; Waisfisz, Q.; van Haelst, M.; Bruijn, M.; Tavares, A.; Mayr, J.A.; Wolthuis, R.M.F.; Oliveira, R. A. * and de Lange, J. * (2022) Biallelic BUB1 mutations cause microcephaly, developmental delay, and variable effects on cohesion and chromosome segregation. Science Advances 8, 10.1126/sciadv.abk0114 * co-corresponding authors
comunicado de imprensa aqui (PT)
press release here (ENG)
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on the news: podcast E=MC2 ; RTP (national tv news); TSF (opening line at national radio news) and several regional, national and international newspapers.
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SELECTED PUBLICATIONS
CARVALHAL, S; et al.; Oliveira, RA. 2018. A quantitative analysis of cohesin decay in mitotic fidelity. J Cell Bio 217 (10): 3343-3353. PMID: 30002073. Selected for a Special Collection of outstanding articles about the cell biology of chromosome organization and segregation, curated by Daniela Cimini and Melina Casadio.
CARVALHAL, S; Stevense, M.; et al. Jessberger, R.; Griffis, E.R. 2017. ALADIN is required for the production of fertile mouse oocytes. Mol Biol Cell. 28 (19): 2470-2478. PMID: 28768824. Co-first authors. Co-corresponding author.
CARVALHAL, S; et al. Griffis, E.R. 2015. The nucleoporin ALADIN regulates Aurora A localization to ensure robust mitotic spindle formation. Mol Biol Cell. 26 (19): 3424-3438. PMID: 26246606.